Karya Tulis Mahasiswa
PERBEDAAN KADAR LOW-DENSITY LIPOPROTEIN (LDL) PADA LAKI-LAKI DEWASA MUDA PEROKOK DAN BUKAN PEROKOK DI POLTEKKES KEMENKES KENDARI
Introduction: Smoking is a risk factor that can affect lipid metabolism due to exposure to nicotine, tar, and carbon monoxide. Nicotine can increase lipolysis and the formation of Very Low-Density Lipoprotein (VLDL), which is then converted to Low-Density Lipoprotein (LDL), thereby increasing LDL levels in the blood and increasing the risk of cardiovascular disease. Objective: To determine the differences in Low-Density Lipoprotein (LDL) levels in young adult male smokers and non-smokers at the Ministry of Health Polytechnic of Kendari. Methods: This study used an observational analytical design with a cross-sectional approach. The sample size was 50 respondents, consisting of 25 smokers and 25 non-smokers who met the inclusion criteria. LDL levels were examined using an enzymatic colorimetric method using a photometer. Data were analyzed using the Mann-Whitney test. Results: The mean LDL level in the smoker group was 181.28 mg/dL, whereas in the non-smoker group, it was 125.56 mg/dL. In the smoker group, 1 individual (4%) had normal levels and 24 (96%) had abnormal levels, while in the non-smoker group, 17 individuals (68%) had normal levels and 8 (32%) had abnormal levels. The Mann-Whitney test result showed a p-value of 0.000 (p < 0.05). Conclusion: There was a significant difference in Low-Density Lipoprotein (LDL) levels between young adult male smokers and nonsmokers at the Kendari Ministry of Health Polytechnic. LDL levels were higher in the smoker group than in the nonsmoker group.
Keywords: Low-Density Lipoprotein (LDL), smokers, non-smokers, young adults, lipid profile.
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